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- $Unique_ID{BRK00575}
- $Pretitle{}
- $Title{What is Idiopathic Thrombocytopenia Purpura?}
- $Subject{immune blood ITP thrombocytes platelets clotting idiopathic
- Autoimmune Thrombocytopenia Purpura ATP Werlhof's Disease splenectomy}
- $Volume{U-7}
- $Log{}
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- Copyright (c) 1991-92,1993 Tribune Media Services, Inc.
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- What is Idiopathic Thrombocytopenia Purpura?
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- QUESTION: I was diagnosed by my physician approximately six months ago with a
- blood disorder referred to as idiopathic thrombocytopenia purpura (ITP). I've
- been unable to find sufficient reading material regarding this disease. Any
- information would be helpful. I am currently in remission.
-
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-
- ANSWER: Whenever faced with these gigantic medical terms, we can learn a bit
- by explaining them piece by piece. Let's start at the end. A "purpura" is a
- purple or reddish brown discoloration seen through the skin, caused by blood
- hemorrhaging into the tissues. In ITP the thrombocytes (platelets), which are
- an important part of the clotting mechanism that controls such bleeding, are
- not present in the blood in normal amounts. Any medical term which ends in
- "penia" means that there is an abnormal reduction in numbers, for "penia"
- comes from the Greek term meaning "poverty". "Idiopathic" means that the
- disease (or pathology) has a spontaneous origin, or more literally an unknown
- cause. The fact is that much is now known about ITP, and that the reason the
- platelets (or thrombocytes) are few in number is that they are being destroyed
- by an immune factor (antibody). Thus we now call the disease "Autoimmune
- Thrombocytopenia Purpura" (ATP) or by an older name, Werlhof's Disease. In
- one of those interesting stories that makes medicine so fascinating, in 1951
- an American hematologist, William Harrington, who believed there was an
- immunological explanation for the disease, injected himself with plasma from a
- patient and developed the disease himself. A good deal of research is going
- on to explain all the mechanisms of the disease, and it can be treated with
- large doses of corticosteroid (cortisone-like medication), as well as other
- medications, with great success. When medications fail to produce the desired
- results, splenectomy, or removal of the spleen, may be considered. Now that
- you have some new insight, and a few more terms to search for, I hope your
- reading will be more rewarding. The fact that you are currently in remission
- is an excellent sign, but as you have probably been told, does not represent a
- permanent state.
-
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-
- The material contained here is "FOR INFORMATION ONLY" and should not replace
- the counsel and advice of your personal physician. Promptly consulting your
- doctor is the best path to a quick and successful resolution of any medical
- problem.
-